Axin: A Master Scaffold for Multiple Signaling Pathways
نویسندگان
چکیده
منابع مشابه
Axin: a master scaffold for multiple signaling pathways.
Axin was originally identified from the characterization of the Fused locus, the disruption of which leads to duplication of axis and embryonic lethality. It is a multidomain protein that interacts with multiple proteins and functions as a negative regulator of Wnt signaling by downregulating the beta-catenin levels. Recently, it was demonstrated that Axin also plays an important role in a JNK ...
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ژورنال
عنوان ژورنال: Neurosignals
سال: 2004
ISSN: 1424-862X,1424-8638
DOI: 10.1159/000076563